research medical center

Shwachman-Diamond America awards grants up to $10,000 for Shwachman-Diamond Syndrome Research. Some larger grants are also available through this 501 (c) 3 non-profit group. Shwachman-Diamond America not only supports Shwachman-Diamond Syndrome research, but it also supports Shwachman-Diamond Syndrome Education.

Shwachman-Diamond America's Mission:

• Fund and promote research in all aspects of SDS.
• Disseminate current medical literature to families and physicians.
• Help fund the biennial International Congress on SDS.
• Facilitate the development of a medical management plan.
• Promote parent education through a family support network.

If you are a researcher and are interested in submitting a grant proposal for an Alex Turnquist Memorial Research Grant, the following are the guidelines:

Shwachman-Diamond America awards Alex Turnquist Memorial Research grants up to $10,000. Grant proposals are accepted throughout the year. SDA does not have a grant request form.

Shwachman-Diamond America requires that the grant proposal be in writing and include the following:

1. Name of Applicant, Principal investigator, project title and summary of proposed investigation (include specific aims, significance and background, any preliminary studies...)
2. A detailed description of your hypothesis/hypotheses and proposed methodologies
3. Relevance of the research to Shwachman-Diamond Syndrome
4. Biographical information on the principal investigator and co-principal investigator, if relevant
5. A detailed budget sheet (grants are available up to $10,000)
6. Statement of facilities available
7. A starting date for the project

General Conditions for the Awarding of Alex Turnquist Memorial Research Grants:

1. The board wishes to receive periodic progress reports. They need not be lengthy. These reports will help Shwachman-Diamond America give updates to our donors, allow evaluation of progress by our medical advisor and assist SDA in future fundraising efforts.
2. Any publications distributed as a result of your research should give proper reference to Shwachman-Diamond America.

You can submit a grant proposal by emailing the Word or PDF file to: shwachmandiamondamerica@embarqmail.com or via regular mail:

Shwachman-Diamond America

931-B South Main Street #332

Kernersville, NC 27284

If you need more information, you can visit the Shwachman-Diamond America website or contact Pattie Curran at 336-423-8158.

What is Shwachman-Diamond Syndrome?

Shwachman-Diamond Syndrome (SDS), first described in 1964, is a rare, genetic (autosomal recessive), multi-systemic disorder affecting the pancreas, bone marrow, and skeleton. The most common symptoms are pancreatic dysfunction (malabsorption), low neutrophil count and short stature. Other organs may also be involved in some SDS patients. Shwachman-Diamond Syndrome affects people differently and not all people with SDS have all of these symptoms. In Infancy, the first symptoms are usually loose, foul smelling, greasy stools and failure to gain weight and grow normally. The pancreas fails to produce the enzymes essential to digest food properly. Because of the exocrine pancreatic dysfunction (malabsorption), the child does not absorb enough nutrients, most commonly the fat-soluble vitamins, to grow and develop normally. Oral enzyme replacement therapy helps these children to digest their food, but many still need to take special vitamin supplements. Improving nutritional status does not necessarily improve the growth of children with Shwachman-Diamond Syndrome.

The bone marrow, where blood cells are produced, is also affected in Shwachman-Diamond Syndrome. White blood cells, which fight infection, are most commonly affected. Neutropenia is the most common hematological abnormality in SDS, though all blood cell lines may be affected. Anemia and blood clotting problems are also common in SDS patients. Because of the bone marrow dysfunction, these children are at a greater risk of developing life-threatening infections. Shwachman-Diamond Syndrome is considered to be a bone marrow failure syndrome, because up to 30% of these children will develop leukemia or aplastic anemia.





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stem cell research

The late actor Christopher Reeve was a tireless advocate of stem cell research in the last decade of his life. Paralyzed from the neck down by a horseback riding accident in 1995, Reeve dedicated his considerable talents and impressive network of powerful allies to attempt to drive forward stem cell research into the reparation of spinal cord injuries and disorders. Despite his continued acting and directing, advocacy of stem cell research became his primary professional and political focus until his death from heart attack in October 2004, nearly ten years after the accident that paralyzed him.

Reeve held an absolute, unwavering belief that the answers to irreversible spinal cord damage lay in the utilization of this controversial potential therapy. He was undaunted by his own physical limitations when fighting for enhancement of government funding into stem cell research, rather, he used his condition as an extremely effective tool when presenting his case to legislative bodies, funding organizations, and media outlets.

Is it possible that the fruits of the efforts of Christopher Reeve, and those working with him to keep stem cell research on the front burners of scientific discovery and legislative calendars, are finally finding themselves ready to be collected? Perhaps not quite, but this week there is evidence that seeds have at long last been planted that may soon grow into the trees of knowledge that may bare those fruits. And, with a little luck, those trees may grow swiftly.

Exciting new evidence about the viability of stem cell therapy for the treatment of patients living with paralysis has just been published by researchers at the Johns Hopkins University Medical School. In a study published in Annals of Neurology, the medical journal of the American Neurological Association, researchers led by Dr. Douglas Kerr studied rats that had been paralyzed and then injected with embryonic stem cells from mice. The resulting study showed that 11 of the 15 mice treated with the therapy regained significant mobility and motor function in the paralyzed limbs.

In light of this groundbreaking research, and the potential that this unprecedented study has to spark new life into the contentious and often avoided political bugaboo, could a change in the public and political response to the stem cell question be at hand? The push called for by Christopher Reeve and others for increased government funding for stem cell research may have been waiting for a banner breakthrough that could infuse skittish governmental and corporate agencies with a little more nerve. Several public interest groups and private religious organizations have effectively made the issue of stem cell research such a political hot potato that advancements have been seriously crippled by the nervous politicians’ slow response to requests for research funding. Could the work of researchers like Dr. Kerr provide that “ah ha!” moment that will nudge the reticent voters into a more corporeal and vocal support of the research efforts?

Governmental funding for stem cell research is supported by a majority of U.S. citizens. In an August 2005 Gallup Poll, in responding to the question "do you think the federal government should or should not fund research that would use newly created stem cells obtained from human embryos?" 56% of people responded that they should, while only 40% responded that they should not. One month earlier, in a poll conducted by CBS News, when asked “do you approve or disapprove of medical research using embryonic stem cells?” 56% of respondents indicated that they approved, while only 30% responded in the negative.

The work of Dr. Kerr and his associates at Johns Hopkins has been on the stem cell radar for several years now. In a 2001 interview with CNN, Christopher Reeve discussed his optimism for the research being conducted, and reiterated his concern about the effects of lackluster governmental funding for their work.

“What a couple of researchers did recently is proof of principle, which is very, very important,” said Reeve. “It was Dr. Gerhard and Dr. Kerr at Johns Hopkins, and they were able to inject mice or rats with a virus, which simulates ALS. They then injected human embryonic stem cells. Then, over a period of time, the progression of deterioration was stopped, and all the rats showed recovery of function,” he stated.

“Now, that is proof, because some people say, well, we don't know what embryonic stem cells can do; it's never been proven. Well, that's a huge first step,” continued Reeve. “And of course we won't know what they can do until we go and do the work. But the work must not be stopped, absolutely.”

That research described by Reeve in the CNN interview has now advanced to the point that researchers have been able to stimulate the reconnection of the muscles to the spinal cord with the embryonic stem cells of mice.

Still, political trepidation continues. Despite the impressive polling numbers in favor of stem cell research, the Stem Cell Research Enhancement Act of 2005, introduced the year after Christopher Reeve’s death, has been stalled in the U.S. senate for nearly a year. The bill, which would lift many of the current limitations on stem cell research that currently slow down the progress of the research and restrict the money the government puts into it, has polled incredibly well, and garnered strong bi-partisan support at its introduction.

In May 2006, the American Diabetes Association, who, like Christopher Reeve and other paralysis patients, also has a strong interest in stem cell research, spoke out about the lag time in passing the bill. The ADA publicly admonished the U.S. Senate for dragging its feet, and demanded to know just when the bill would be passed.

If Christopher Reeve were alive today to see the most recent results of the work of Dr. Kerr and his associates at Johns Hopkins, he would certainly be encouraged by current advancement in stem cell research, despite the lackluster funding and slow response to stem cell legislation. Now that advancements in the research are more tangible, perhaps the funding restrictions will be loosened and the work of advocates like Christopher Reeve will be honored. Should that happen, the reversal of paralysis due to spinal cord injuries and disorders may be closer at hand. The new research out of Johns Hopkins has certainly taken us several steps closer.





Reference research: research Dr. and home research and general research and recent update




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research methods in physical activity

Shwachman-Diamond America awards grants up to $10,000 for Shwachman-Diamond Syndrome Research. Some larger grants are also available through this 501 (c) 3 non-profit group. Shwachman-Diamond America not only supports Shwachman-Diamond Syndrome research, but it also supports Shwachman-Diamond Syndrome Education.

Shwachman-Diamond America's Mission:

• Fund and promote research in all aspects of SDS.
• Disseminate current medical literature to families and physicians.
• Help fund the biennial International Congress on SDS.
• Facilitate the development of a medical management plan.
• Promote parent education through a family support network.

If you are a researcher and are interested in submitting a grant proposal for an Alex Turnquist Memorial Research Grant, the following are the guidelines:

Shwachman-Diamond America awards Alex Turnquist Memorial Research grants up to $10,000. Grant proposals are accepted throughout the year. SDA does not have a grant request form.

Shwachman-Diamond America requires that the grant proposal be in writing and include the following:

1. Name of Applicant, Principal investigator, project title and summary of proposed investigation (include specific aims, significance and background, any preliminary studies...)
2. A detailed description of your hypothesis/hypotheses and proposed methodologies
3. Relevance of the research to Shwachman-Diamond Syndrome
4. Biographical information on the principal investigator and co-principal investigator, if relevant
5. A detailed budget sheet (grants are available up to $10,000)
6. Statement of facilities available
7. A starting date for the project

General Conditions for the Awarding of Alex Turnquist Memorial Research Grants:

1. The board wishes to receive periodic progress reports. They need not be lengthy. These reports will help Shwachman-Diamond America give updates to our donors, allow evaluation of progress by our medical advisor and assist SDA in future fundraising efforts.
2. Any publications distributed as a result of your research should give proper reference to Shwachman-Diamond America.

You can submit a grant proposal by emailing the Word or PDF file to: shwachmandiamondamerica@embarqmail.com or via regular mail:

Shwachman-Diamond America

931-B South Main Street #332

Kernersville, NC 27284

If you need more information, you can visit the Shwachman-Diamond America website or contact Pattie Curran at 336-423-8158.

What is Shwachman-Diamond Syndrome?

Shwachman-Diamond Syndrome (SDS), first described in 1964, is a rare, genetic (autosomal recessive), multi-systemic disorder affecting the pancreas, bone marrow, and skeleton. The most common symptoms are pancreatic dysfunction (malabsorption), low neutrophil count and short stature. Other organs may also be involved in some SDS patients. Shwachman-Diamond Syndrome affects people differently and not all people with SDS have all of these symptoms. In Infancy, the first symptoms are usually loose, foul smelling, greasy stools and failure to gain weight and grow normally. The pancreas fails to produce the enzymes essential to digest food properly. Because of the exocrine pancreatic dysfunction (malabsorption), the child does not absorb enough nutrients, most commonly the fat-soluble vitamins, to grow and develop normally. Oral enzyme replacement therapy helps these children to digest their food, but many still need to take special vitamin supplements. Improving nutritional status does not necessarily improve the growth of children with Shwachman-Diamond Syndrome.

The bone marrow, where blood cells are produced, is also affected in Shwachman-Diamond Syndrome. White blood cells, which fight infection, are most commonly affected. Neutropenia is the most common hematological abnormality in SDS, though all blood cell lines may be affected. Anemia and blood clotting problems are also common in SDS patients. Because of the bone marrow dysfunction, these children are at a greater risk of developing life-threatening infections. Shwachman-Diamond Syndrome is considered to be a bone marrow failure syndrome, because up to 30% of these children will develop leukemia or aplastic anemia.





Reference research: research Dr. and home research and sport research and my social page




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research methods in education 9th edition

You might be overwhelmed on how to research information for your book. It may be difficult in the beginning to know where to start at or even how to gather information. How to research information for your book is quite simple when you follow some steps. You need to write down a list of all of certain information that you want to be included in your book. Here are five tips on how to research information for your book.

1.Talk to experts. Make sure to put experts on that list to get information from. You want to be able to quote information and check facts with experts. Experts will add more value to the information in your book and also provide you with additional information. They are also great to get to know since you can learn more information from them. You want to write down their names correctly.

2.Get a tape recorder. You want to get a tape recorder when asking experts questions. The tape recorder will help you later on when you putting the information together in your book. It is also important to take notes while talking to the experts, but the tape recorder will help you pick up any information that you may have missed due to the person talking too fast or not being able to write fast enough.

3.Get a digital camera. You want a digital camera to take pictures for your book. A digital camera with pictures also may be able to help you describe something in your book better depending upon what topic your book is about. They are nice to have a picture to look at in order to put words regarding the picture.

4.Go to the library in your city. The library is the perfect way to get information regarding the topic of your book. You can also check current old and new information this way. Your library might be also to order a book for you if you can't find it in the library. Library is a great source to get allot of information for free without having to buy a ton of books. A library usually offers Internet access for free to find additional information. Make sure to check out the college library in your local area too. One thing that is great about a library is that they usually have old copies of newspapers.

5.Talk to neighbors and other people. Depending upon the topic of your book you can learn quite a bit of information from neighbors and other people. People will be glad to tell you information for free just to be able to see their name in your book. If you any people that are professionals in a certain field that you can use that opportunity to talk to them.

When gathering information then please make sure to keep it organized so you can keep track of it better. It may help to have file folders to keep everything separated so it doesn't get all mixed up. Out of all the information in your book the experts are the most important of it all. The experts makes your book hold more weight as far as being more accurate and also contains more knowledge so it is even more helpful to others.




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